In 2010, Davis appeared in David Schwimmer's Trust, about a young girl who is sexually assaulted by an online predator. The movie was built upon Schwimmer's years-long affiliation with The Rape Foundation, the founder of which was portrayed by Davis in the movie. The experience of starring in that film, as well as her own real-life experiences with sexual assault, inspired Davis to become an advocate for the organization. She told attendees of a fundraiser for the organization (via CBS News), "Myself, my mother, my sisters, my friend Rebecca, my friend from childhood, we all have something in common: We are all survivors of sexual assault in some shape or form." She then shared the harrowing story of how her own sister Danielle was assaulted at just eight years old by a habitual assailant whose punishment was minimal. And that her sister had — perhaps as a consequence — suffered a life of addiction and prostitution ever since.
The organization provides medical, counseling, and legal services to victims of sexual crimes. Davis delivered a powerful speech on their behalf, saying (via People), "Living out loud is not playing Annalise Keating on How To Get Away With Murder, it's not being Amanda Waller in Suicide Squad, it's not getting an Oscar. Living out loud is living a life that's bigger than yourself. Living out loud is long after you're gone – and trust me, everyone in this room, you're going to be dead a lot longer than you're alive even if you live to be 100 years old – you leave something on this Earth that's bigger than yourself. And that's a big message in this town."