Before & After Photos Of Kelly Osbourne's 'Ozempic Face' Are Jarring
Celebrities with so-called "Ozempic face" have become a common feature of the mid-2020s thanks to the rise of injectable GLP-1 receptor agonists, which include weight loss medications like Wegovy, Mounjaro, Zepbound, and, of course, Ozempic. Many of our favorite stars have shed pounds at alarming rates, sometimes stepping out with hollow appearances due to the sunken cheeks and more prominent bones and wrinkles caused by rapid weight loss. Nepo baby and TV personality Kelly Osbourne has become a supreme example of this trending facial look throughout her weight loss journey.
Osbourne's weight has fluctuated greatly. Diet, exercise, and a gastric sleeve surgery in 2018 led to Osbourne dropping nearly 100 pounds, but she gained it back during her pregnancy. The "Fashion Police" alum used to flaunt a fuller look to her face, with a round chin, smooth skin, full lips, and still some baby fat in her cheeks. Usually known for her playful aesthetic, Osbourne rocked dyed purple hair and a heavy makeup style that complemented it. However, by 2025, that playful vibe began to take a backseat, and so did her rounder, softer features, leading to the Ozempic rumors. After all, she lost another 85 pounds.
Osbourne lost the fullness of her cheeks, gaining more angular cheekbones and smaller cheek apples. Her nose and chin became sharper, as well, likely due to the body sculpting treatments she has admitted to. and her lips lost their plumpness (except during times when she has obviously used filler or something similar). While Osbourne has flat-out denied using Ozempic (or having plastic surgery), many critics have pointed to the singer's eyes and eyebrows, as well as her mouth and cheekbones, as obvious signs of the medication.
Osbourne was criticized throughout her weight loss journey
Kelly Osbourne has dealt with haters for a long time, with their negativity often centering on her weight. Like other women who have lost a lot of weight, including Melissa McCarthy, Osbourne just can't win with the haters — the singer was criticized for her fuller figure, but was then critiqued for various reasons once she lost weight.
During a December 2025 episode of Piers Morgan's talk show, the controversial British TV host shared a TikTok video of Osbourne addressing the string of comments she was receiving online. "I don't even know how to say this, so I'm just going to say it: To the people who keep thinking they're being funny and mean by writing comments like 'Are you ill,' or 'Get off Ozempic,' or 'You don't look right' — My dad just died, and I'm doing the best that I can, and the only thing I have to live for right now is my family," Osbourne told the haters while mourning the loss of her father, Ozzy Osbourne.
@piersmorganuncensored "She can't eat right now!" Sharon Osbourne discusses her daughter Kelly being trolled over her appearance: "It's a shield for people that are unhappy." #kellyosbourne #sharonosbourne #ozzyosbourne #PiersMorgan #PiersMorganUncensored #fyp #news
♬ original sound – piersmorganuncensored – piersmorganuncensored
In fitting Osbourne fashion, the star ended her response by saying, "So, to all those people, f*** off!" Nonetheless, Osbourne has admitted to going a bit far with her dieting. As she said during an appearance on the Scheananigans with Scheana Shay podcast, "I was on a mission after having the baby to lose all my baby weight. And then I was like, well, I lost all the baby weight, let's see how far I can go with it. [I] went a little bit too far but stopped." As long as she's happy.