Before & After Pics Of Amy Schumer Make Her 'Ozempic Face' Obvious
There's no denying that Amy Schumer has undergone a stunning transformation over the years, but none is more shocking than her weight loss journey. In 2025 Schumer admitted to having tried several GLP-1 medications, from Wegovy to Mounjaro. According to Page Six, it was eventually the latter that helped her lose 50 pounds, and as much as Schumer herself has insisted that she didn't lose the weight "to look hot," there's ample evidence she's enjoying the results. As Schumer takes to Instagram to repeatedly document her new looks and dole out messages to her haters, she's also revealing her obvious "Ozempic face."
When losing a significant amount of weight, the body and face shift. However, with the drastic and quick weight loss aided by GLP-1 use, cheeks can appear drawn, skin can become looser, and the overall appearance looks slightly fragile. Of course, the "Trainwreck" star has come out as saying that she struggles with Cushing Syndrome and that her weight loss was attached to her health, not vanity. While there's plenty of room for this to be the case, Schumer's drastic transformation also came on the heels of another big change in her life, causing many to speculate about what was really going on.
Amy Schumer's weight loss coincided with her divorce
There had been rumors that Amy Schumer's marriage to Chris Fischer was crumbling, which all came to a head at the end of 2025. After Schumer emptied her Instagram account of any and all photos, seemingly an attempt at getting a new slate, many were quick to point out that it could be a two-fold opportunity. Not only was it a failsafe to rid the internet of any photos of Fischer, it also scrubbed old photos before Schumer lost a significant amount of weight. This led many to suggest that Schumer's weight loss had something to do with her separation from Fischer.
As much as the "Kinda Pregnant" star might want to claim that her bodily transformation and personal shifts are separate, the evidence is not stacked in her favor. It's especially hard to ignore when Schumer keeps posting photos of her revenge body as often as possible. In a since-deleted Instagram post, Schumer showed off her physique yet again by posing in a series of swimsuits, captioning the post in part by saying her future "is about self care and self love" (via Page Six). Her insistence that her transformation is purely personal doesn't really check out. However, there's no denying that the "Unfrosted" actor is enjoying her new beginnings.